Update: A woman has sadly died https://wearesouthdevon.com/police-appeal-for-witnesses-following-fatal-m5-crash/
Update 14:45 Highways agency have just posted to Twitter:
https://twitter.com/HAtraffic_swest/status/560085415936671747
A section of the M5 remains closed following a serious collision involving a car and lorry.
Police and other emergency services are at the scene of a serious collision on the M5 northbound near Cullompton.
Officers were called just after 12.10pm on Tuesday 27 January after reports of a collision between a car and a lorry, about one mile before junction 28, Cullompton.
The female car driver has been seriously injured. Reports suggest that she was airlifted to hospital.
The extent of injuries of the other occupants in the vehicle and the lorry driver are not yet known.
The northbound carriageway has been closed between Exeter, junction 29, and Cullompton.
The M5 is expected to be closed for several hours. Motorists are advised to avoid the area and find alternative routes.
https://twitter.com/thetvdetective/status/560084040020410368